Vaccines R&D-2019
About Conference
Vaccines Committee delighted to welcome all the interested and enthusiastic participants across the globe to its prestigious ‘2nd European Congress on Vaccines R&D & Vaccination’ to be held during July 11-12, 2019 at Prague, Czech Republic. Which highlights the theme “Optimizing Vaccination Strategies for control and elimination of Immunizing Infections”. Vaccines R&D-2019 is a two-day conference concentrating on Interactive Sessions & Sub-sessions emphasized on innovation and new trends on vaccines, keynote lectures from Senior Scientists and industry experts, panel discussions, poster competitions, and Young Researcher Forum. The conference program will feature well-known and thought to provoke speakers in interactive discussion sessions, prompt keynote presentations, Oral talks, Poster presentations, and Exhibitions.
Why attend??
The Vaccine R&D & Vaccination conference interacts with members across the globe focused on learning about vaccines and its specialties. This is the single best opportunity to reach the largest participants. Sharing the knowledge and demonstrations, information and B2B meetings with industrialists and potential clients to make a splash with innovative products live and brand recognition at this event. World-renowned speakers, the most recent techniques, and the latest updates on vaccines are hallmarks of this conference.
EuroSciCon is the longest running independent life science events company with a predominantly academic client base. Our multi-professional and multi-specialty approach creates a unique experience that cannot be found with a specialist society or commercially.
For Universities, Associations & Societies:
- Association Partnering
- Collaboration proposals
- Academic Partnering
- Group Participation
For Students & Research Scholars:
- Poster Competition (Winner will get Best Poster Award)
- Young Researcher Forum (YRF Award to the best presenter)
- Student Attendee
- Group Registrations
For Business Delegates:
- Speaker Presentations
- Symposium hosting
- Book Launch event
- Networking opportunities
- Audience participation
For Companies:
- Exhibitor and Vendor Booths
- Sponsorships opportunities
- Product launch
- Workshop organizing
- Scientific Partnering
Marketing and Networking with clients
Euroscicon organizes International Vaccine Meetings annually across Europe, Austria, Ireland, Germany, France, Liechtenstein, Lithuania, Finland, Luxembourg, Hungary, Italy, Norway, Poland, Denmark, Macedonia, Greece, Portugal, Romania, Czech Republic, Switzerland, United Kingdom, Belgium, Scotland, Latvia, Ukraine, Sweden, Denmark, Spain, Netherlands Russia, Bulgaria, France, with solitary subject of quickening logical revelations.
Session/Tracks
The long-term aim is to develop a nontoxic and effective vaccine that defends people worldwide after getting infected with HIV. However, even if a vaccine only defends some people who get vaccinated, or even if it affords less than total protection by reducing the threat of infection, it could still have a major impact on the rates of transmission and help control the pandemic, particularly for populations at high risk of HIV infection. A partially effective vaccine could decrease the number of people who get infected with HIV, further reducing the number of people who can pass the virus on to others. By considerably reducing the number of new-fangled infections, we can stop the widespread.
- HIV Vaccine Strategies
- T cell-based Vaccines
- B cell-based Vaccines
- Innate & Mucosal Immunity
- Viral Vaccine Vectors
The principal course of rabies treatment was controlled under the supervision of Louis Pasteur, over a century back. From that point forward, rabies immunizations have dependably been among the first to profit by advance underway and control. As respects immunizations for human use, around 1955 there was a change from antibodies arranged from creature nerve tissue to embryonated eggs and soon a short time later, around 1960, to adjustment of rabies infection to societies of human diploid cells. The improvement of this antibody, which remains the reference immunization in relative investigations of immunogenicity, took long years. It was first enlisted in France in 1974 and somewhat later in North America. The late 1970s and the 1980s saw the advancement of a plenty of immunizations arranged on different cell substrates, for example, essential explant cells of hamster, canine or fetal calf kidney, fibroblasts of chicken developing life, or diploid cells from rhesus monkey fetal lung, lastly cells from nonstop lines (Vero cells). The creation of some of these immunizations was ceased toward the finish of the 1980s while others have been controlled to a huge number of patients.
- Tuberculosis Vaccine
- Bordetella Vaccine
- OPV (Oral Poliovirus Vaccine)
- Meningococcal /Menactra Vaccines
- Smallpox Vaccine
- Rotavirus Vaccine
3. Preventable Disease Vaccines
An antibody preventable sickness is an irresistible malady for which a compelling preventive immunization exists. On the off chance that a man procures an immunization-preventable ailment and passes on from it, the demise is viewed as an antibody preventable passing.
- Diphtheria
- Haemophilus influenzae serotype b disease
- Meningitis
- Tuberculosis
- Yellow fever
- Mumps
- Measles
Immunization is an imperative piece of the family and general wellbeing. Immunizations keep the spread of infectious, unsafe, and even fatal ailments. These incorporate measles, polio, mumps, chicken pox, challenging hack, diphtheria, and HPV. The primary genuine immunization found was the smallpox antibody. Smallpox was a lethal sickness a century prior. It slaughtered 300 million to 500 million individuals around the globe in the twentieth century alone. The immunization was given to numerous individuals. The malady was in the end deleted from the earth. It is the main malady to be totally obliterated. There are presently others near that point. These incorporate polio and mumps. Without the smallpox antibody, numerous more individuals would definitely kick the bucket. Rather, we don't should be inoculated for it any longer. This is the thing that immunizations can do.
- Routes of Administration
- Economics of Vaccination
- Opposition to Vaccination
The main objectives of veterinary immunizations are to advance the wellbeing and welfare of companion creatures, increment making of domesticated animals in a sparing way, and stay away from creature to-human transmission from together local creatures and untamed life. These diverse points have assimilated to assorted strategies to the advance of veterinary antibodies from unrefined in the past valid entire pathogen arrangements to molecularly unmistakable subunit immunizations, on a very basic level built animals previously figments, vectored antigen definitions, other than stark-bare DNA infusions. The last productive result of antibody examination and improvement is the age of an item that will be available in the commercial centre or that will be utilized as a part of the field to achieve wanted results. As itemized in this survey, fruitful veterinary antibodies have been delivered in inconsistency of viral, bacterial, protozoal, and multicellular pathogens, which in numerous behaviours have driven the field in the application and variety of novel advancements. These veterinary immunizations have devoured, and keep on having, a noteworthy effect on creature prosperity and generation as well as on human wellbeing through expanding innocuous nourishment supplies and anticipating creature to-human communicate of irresistible infections. The proceeded with connection amongst creatures and human analysts and wellbeing experts will be of real significance for acquainting new advancements, giving creature models of ailment, and undermining new and developing irresistible infections.
- Efficacy of Veterinary Medicine
- Animal Health Outcomes
- Recent Advances in Animal Vaccination
- Current Status of Veterinary Vaccines
- Vaccines for Livestock Diseases
6. Clinical Trials on Vaccines
As new advancements and customized antibodies turn into the standard, the dynamic of clinical preliminaries needs to develop. This engaged clinical advancement meeting will enable you to exhibit your administrations to the individuals who are hoping to run new preliminary models, require bolster in picking and picking up endorsement for various clinical endpoints and need to see how to get the best out of the data gathered.
- Exploratory Stage
- Pre-clinical Stage
- Clinical development
- Regulatory review and approval
- Manufacturing
- Quality Control
7. Vaccine Safety and Efficacy
For the past two centuries, vaccines have provided a safe and effective means of preventing a number of infectious diseases. Although the safety of some vaccines has been questioned in recent years, the currently available vaccines are more than a millionfold safer than the diseases they are designed to prevent. Vaccines, however, should always be used in conjunction with other public health interventions. One important intervention is education because the general public can be led to believe that vaccines are unsafe and not needed by misinformation readily available electronically and in print. Not only are some vaccines available via injection but other vaccines are also given orally or intranasally. New vaccines are being studied for topical and intravaginal use. In addition, new systems are being developed for more efficient production of vaccines, especially for influenza. Vaccines are currently available for only a limited number of viral and bacterial diseases. In the future, it is anticipated that safe and effective vaccines will be developed against a number of other viral and bacterial infections as well as fungal and protozoan diseases.
- Vaccines: A boon or curse
- Adverse Drug Reactions
- Vaccine Safety Programs
- Development of Pandemic Vaccines
- Current Issues
- Vaccine Preventable Diseases
- Vaccine Pharmacovigilance
8. Vaccine Research and Development
Antibody Research and Development includes immunization investigate in the field of irresistible maladies in the aggregate reconciliation, including growth, AIDS and allergies. New immunizations are always being looked into and created. There has been a relentless movement in the progression of immunizations that has prompted advancement of authorized vaccines. Combination antibodies have been presented which can keep a few illnesses immediately. Hazard profile of antibody against unending maladies is modestly high when contrasted with those against intense infections.
- Vaccine Research in Europe
- Therapeutic Vaccination for Auto Immune Diseases
- Vaccine Management & Quality Assurance
- Vaccine Clinical Trials
- Vaccine Discovery, Development and Formulation
Viral hepatitis is a genuine medical issue everywhere throughout the world. Notwithstanding, the decrease of the bleakness and mortality because of immunizations against hepatitis A and hepatitis B has been a noteworthy segment in the general lessening in antibody preventable infections. We will examine the study of disease transmission, immunization advancement, and post-inoculation impacts of the hepatitis A and B infection. Furthermore, we examine endeavours to give hepatitis D antibody to the 350 million people tainted with hepatitis B all around. Given the absence of a hepatitis C antibody, the numerous difficulties confronting the generation of a hepatitis C immunization will be appeared, alongside present and previous inoculation trials. As there is no present FDA-endorsed hepatitis E immunization, we will introduce inoculation information that is accessible in whatever is left of the world. At last, we will talk about the current difficulties and inquiries confronting future undertakings for every one of the hepatitis infections, with endeavours proceeding to centre on significantly diminishing the dismalness and mortality related with these genuine contaminations of the liver.
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
Such a great amount of action around disease antibodies and immunotherapy at this moment, would you be able to bear to pass up a major opportunity? It is where the worldwide market will meet up to share the most recent in beginning time logical headways, present clinical preliminary information, talk about new plans of disease immunizations and evaluate the fate of blend medications. Ensure that individuals know about the work you are doing to put yourself at the front line of the business.
- Monoclonal antibodies to treat Cancer
- Cancer Vaccines
- Cancer Immunotherapy
- CAR T-Cell Therapies
Flu is a genuine ailment that can prompt hospitalization and in some cases even passing. Each influenza season is extraordinary, and flu disease can influence individuals in an unexpected way, yet a large number of individuals get this season's flu virus consistently, a huge number of individuals are hospitalized and thousands or countless individuals kick the bucket from influenza-related causes each year. Indeed, even solid individuals can become ill from this season's cold virus and spread it to others. CDC assesses that influenza-related hospitalizations since 2010 went from 140,000 to 710,000, while influenza-related passings are evaluated to have extended from 12,000 to 56,000. Amid influenza season, influenza infections flow at more elevated amounts in the U.S. populace. ("Influenza season" in the United States can start as ahead of schedule as October and last as late as May.) A yearly regular influenza antibody is the most ideal approach to lessen your danger of becoming ill with occasional influenza and spreading it to others. At the point when more individuals get inoculated against this season's cold virus, less influenza can spread through that network.
- Live Attenuated Influenza Vaccine
- Quadrivalent Influenza Vaccine
- Flu Blok seasonal Influenza Vaccine
An immune response is a natural arranging that gives dynamic picked up invulnerability to a particular ailment. The master energizes the body's safe system to see the administrator as a peril, wreck it, and keep a record of it, so the resistant structure would all be able to the all the more easily see and beat any of these littler scale life shapes that it later encounters. An immunization is the implantation of an executed or incapacitated animal that produces invulnerability in the body against that living thing. An immunization is the methodology by which a man or animal gets the opportunity to be protected from a disease Vaccines cause vaccination, and there are moreover a couple of infirmities that reason inoculation after an individual recovers from the ailment. Antibodies work genuinely well. Clearly, no pharmaceutical is perfect yet most puberty antibodies convey invulnerability around 90-100% of the time.
- Intralymphatic Vaccination
- CD4+ and CD8+ T Cell Responses
- Monoclonal Antibodies
- Vaccines for Routine and Selective uses
13. Mucosal Vaccines
Mucosal tissues (e.g. nasal, oral, visual, rectal, vaginal) cover an extensive surface of the body. It is basic to create methodologies for killing the irresistible specialist at these surfaces since contaminations are started at these destinations. Mucosal inoculation includes the organization of immunizations at least one mucosal locales prompting enlistment of insusceptible reactions at that site, or other mucosal destinations. Vaccination includes the conveyance of antigens to the mucosal invulnerable framework. The antigen conveyance frameworks may involve a straightforward support arrangement with/without adjuvants or a propelled particulate detailing, for example, liposomes or nanoparticles. The most normally assessed course for mucosal antigen conveyance is oral; however different courses have additionally been investigated.
- Edible Vaccines
- Common Vaccination given by Mucosal Route
- Mucosal Vaccines Delivery
- Challenges in Mucosal Vaccine Delivery
Globally, drug addiction is a severe problem. One therapy being considered is vaccines against drugs of abuse. The antibodies obtained against the drug can take up the drug and avert it from reaching the reward center in the brain. Few such vaccines have entered clinical trials, but research is going on rapidly.
- Nicotine vaccines
- Morphine and heroin vaccines
- Drug molecules and immune system
- Linkage chemistry, adjuvants and immunological proteins
- Cocaine vaccines
15. Poultry Vaccines
Inoculation has a vital influence in the wellbeing administration of the poultry rush. There are various sicknesses that are avoided by inoculating the flying creatures against them. An immunization keeps a specific illness by activating or boosting the winged animal's invulnerable framework to create antibodies that thusly battle the attacking causal creatures. A characteristic intrusion that really causes the ailment will have an indistinguishable outcome from the fowl will create antibodies that battles the present attack and also to forestall future attacks by the same causal life forms. Lamentably flying creatures that wind up infected generally progress toward becoming unthrifty, non-beneficial or even bite the dust. A contamination caused by characteristic attack will be uncontrolled and in this manner has the likelihood of causing serious harm; however immunization gives a method for controlling the outcome with insignificant damage to the flying creatures.
- E.coli Vaccines
- Pasteurella multocida vaccines
- Riemerella anatipestifer vaccines
16. Polio Vaccines
Inoculation can shield individuals from polio. Polio is an ailment caused by an infection. It is spread primarily by individual-to-individual contact. It can likewise be spread by expending nourishment or beverages that are tainted with the excrement of a contaminated individual.A great many people contaminated with polio have no indications, and numerous recoup without inconveniences. Be that as it may, here and there individuals who get polio create a loss of motion (can't move their arms or legs). Polio can bring about changeless inability. Polio can likewise cause passing, for the most part by incapacitating the muscles utilized for relaxing.
- Inactivated Polio Vaccine (poliomyelitis)
- Trivalent oral polio vaccine
- Bivalent oral polio vaccine
- Monovalent oral polio vaccines
17. Vaccines for pregnant women and neonates
Immunizations can help keep you and your developing family solid. On the off chance that you are pregnant or arranging a pregnancy, the particular immunizations you require are controlled by elements, for example, your age, way of life, restorative conditions you may have, for example, asthma or diabetes, sort and areas of travel, and past inoculations. The Advisory Committee on Immunization Practices (ACIP) suggests that all youngsters get their first dosage of Hepatitis B antibody during childbirth and finish the antibody arrangement by age 6– year and a half.
- Immunization during or before pregnancy/delivery
- HIV and other STD vaccines for pregnant women
- Influenza vaccination of pregnant women and protection of their infants
- HPB, HAV, HBV vaccination for neonates
- Whooping cough vaccines in pregnant women
- Halting vaccination in pregnancy
- Chiropractic vaccination care in women and pregnancy
18. Fish Vaccines
Inoculation assumes an imperative part in vast scale business angle cultivating. As a rule, exactly created immunizations in light of inactivated bacterial pathogens have turned out to be exceptionally effective in angle. Less industrially accessible viral antibodies and no parasite immunizations exist. Considerable viability information is accessible for new fish immunizations and propelled innovation has been executed. Fish antibodies can be conveyed a similar way we vaccinate warm-blooded creatures. Fish can be inoculated by drenching in antibody for a brief timeframe.
- Oral Vaccination
- Immersion Vaccination
- Injection Vaccination
- Vaccination Techniques
19. Vaccines for Immune mediated diseases
Patients with insusceptible interceded fiery illnesses (IMID, for example, RA, IBD or psoriasis, are at expanded danger of contamination, in part due to the ailment itself, yet for the most part as a result of treatment with immunomodulatory or immunosuppressive medications. Regardless of their hoisted chance for immunization-preventable illness, inoculation scope in IMID patients is shockingly low. This audit condenses current writing information on immunization wellbeing and viability in IMID patients treated with immunosuppressive or immunomodulatory sedates and details beast-hone proposals on inoculation in this populace. Particularly in the present time of organic treatments, including TNF-blocking operators, extraordinary thought ought to be given to immunization techniques in IMID patients. Clinical confirmation demonstrates that inoculation of IMID patients does not increment clinical parameters of illness action. Live immunizations are contraindicated in immunocompromised people; however non-live antibodies can securely be given. In spite of the fact that the lessened nature of the safe reaction in patients under immunotherapy may negatively affect inoculation viability in this populace, satisfactory humoral reaction to immunization in IMID patients has been shown for hepatitis B, flu and pneumococcal immunization. Immunization status is best checked and refreshed before the beginning of immunomodulatory treatment: live antibodies are not contraindicated around then and inactivated antibodies inspire an ideal safe reaction in immunocompetent people.
- Information on the Benefits and Risks of Immunization
- Cost Ratio of Immunization
- Vaccine Schedule and Administration
- Integrity of the Immunization Program
- Global Vaccination and Challenges
- Global and Regional Immunization
- Future Studies
20. Vaccine Supply & Logistics
Comprise a number of tasks and processes generally aiming at developing and implementing growth opportunities within and between organizations. It is a subset of the fields of business, commerce, and organizational theory. Vaccine development programs face several challenges that set them apart from other types of healthcare product development programs.
- Vaccine supply chain logistics
- Vaccines Export and Import
- Vaccine Business and Development
21. Biotechnology and Modern Vaccine Technology
Biotechnology is used in the evolution of vaccine in three different processes: Using a special monoclonal antibody in the segregation of pure antigens, using cloned genes for the synthesis of antigens, synthesized proteins used as vaccines. Recombinant vaccines are vaccines yielded from recombinant DNA Technology. They are also termed as subunit vaccines.
- Hydrophobic Nanoparticle Technology
- TLR Agonists
- Surfaced Arrayed Therapeutics
- Immunopurification
- Synthetic peptides
- Modern vaccine formulation technologies
A recombinant immunization is an antibody delivered through recombinant DNA innovation. This includes embeddings the DNA encoding an antigen, (for example, a bacterial surface protein) that invigorates a resistant reaction into bacterial or mammalian cells, communicating the antigen in these cells and afterward sanitizing it from them.
- DNA vaccines
- Recombinant (protein subunit) vaccines
The vaccines in which the desired genes that encode the antigen protein for a specific disease are introduced into the genome of plant tissue by various methods are termed as plant-based vaccines. The most common procedures that are used to yield effective plant-based vaccines are Agrobacterium-mediated gene transfer and Transformation via genetically modified plant virus. Though, growth in the field of science and technology established new approaches such as agroinfiltration, biolistics, electroporation, polyethylene glycol treatment and sonication to replace the former methods.
- To increase the efficacy of gene delivery
- Plastid Methods transformation
- Immunogen design and gene synthesis
- Plant-based vaccines production
- Challenges of plant-based vaccines
Market Report
Past Conference Report(Euro Vaccines 2018)
PAST CONFERENCE REPORT (Euro Vaccines 2018)
Euro Vaccines 2018: Past Conference Information
Euro Vaccines 2018 Report:
EuroSciCon takes great pride in announcing the success of “Euro Vaccines 2018“ which was held in Budapest, Hungary, during 26-27 October 2018.
EV 2018 witnessed a combination of peerless speakers who enlightened the crowd with their knowledge and confabulated on various new-fangled issues related to the field of Vaccines & Vaccination. The extremely illustrious conference hosted by EuroSciCon was marked with the attendance of young and brilliant researchers, experienced professors, delegates and talented student communities representing their countries around the world.
For EV 2019 Final Program: Click here
The conference aimed with a theme “Drifts in traditional and Innovative Vaccines approaches”. The summit engrossed a vicinity of sensible discussions on subjects like HIV Vaccines | Veterinary Vaccines | Human Vaccines | Research & Development of Vaccines | Preventable Disease Vaccines | Vaccines for pregnant women and Neonates | Sessions: Vaccine Safety & Efficacy | Polio Vaccines | Influenza Vaccination | Mucosal Vaccines | Poultry Vaccines
The two days event implanted a firm relation of upcoming strategies in the field of Vaccines with the scientific community. The conceptual and valid knowledge shared, will also raise organizational collaborations to develop scientific accelerations.
Organizing Committee NDM 2018:
Adel M Talaat, University of Wisconsin-Medison, USA | Satya Parida, The Pirbright Institute, UK | Kathleen Hefferon, Cornell University, USA | Leonardo Saenz Iturriaga, Biomedical Sciences of the University of Chile, Chile | Alexander Suvorov, Institute of Experimental Medicine, Russia | Murice Gatera, Rwanda Biomedical Center, Uganda
The Organizing Committee would like to thank the moderators for their support which resulted in the smooth functioning of the conference.
George Kamkamidze, University of Georgia, Georgia
The conference was boarded with an opening ceremony followed by a series of lectures delivered by both Honorable Guests and members of the Keynote forum.
The best Part of the conference was the keynote forum by prominent scientists gave their profitable contributions in the form of highly enlightening presentations and made the conference a best notch one.
Adel M Talaat, University of Wisconsin-Medison, USA
Satya Parida, The Pirbright Institute, UK
Kathleen Hefferon, Cornell University, USA
Leonardo Saenz Iturriaga, Biomedical Sciences of the University of Chile, Chile
Alexander Suvorov, Institute of Experimental Medicine, Russia
Murice Gatera, Rwanda Biomedical Center, Uganda
EuroSciCon Group is prerogative to thank the Organizing Committee Members, Keynote speakers; Chair and Co-chairs on engross the keynote sessions and YRF and Poster sessions in an expanded manner to make this conference a privileged Summit.
EV 2018 Speaker Line Up:
Speakers:
Mohamed Dilai, Hassan II Institute for Agronomy and Veterinary Medicine-Rabat, Morocco | George Kamkamidze, Suranaree University of Georgia, Georgia | Brian G Hubka, Contamination Prevention Technologies, USA | Ayoub Bazzaz, University of Kerkuk, Iraq | Jeanne Moldenhauer
Young Research Forum (YRF):
Sasmitha Upadhyaya, The Pirbright Institute, UK
Video Presentation:
Giulio Tarro, T. & L. de Beaumont Bonelli for cancer research, Italy
We once again thank all the participants for their wonderful involvement towards the event which helped us for the successful execution of this event.
Let's meet up in the upcoming EuroSciCon Conference on Vaccines R&D-2019.
Learn More
Ludwig Maximilians University Munich, Germany | Charité-Universitätsmedizin Berlin, Germany | Wroclaw Medical University, Wroclaw, Poland | Finnish Institute of Occupational Health, Helsinki, Finland | Technical University Munich, Germany | University of Pisa, Italy | University of Messina, Messina, Italy | University Laboratory of Medical Research-University of Verona, Italy | Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark | Wageningen University, the Netherlands | University Medical Centre Utrecht, The Netherlands | National Institute of Allergy and Infectious Disease | University of Bologna, Bologna, Italy | Clermont-Ferrand, France | Imperial College London, London | Manchester Institute of Biotechnology | University Hospitals of Geneva and University of Geneva, Geneva, Switzerland | Centre for HIV Research | Zealand University Hospital, Denmark | Odense University Hospital, Denmark | Aarhus University, Denmark | Tampere University Hospital, Tampere, Finland | University of Tampere School of Medicine and Fimlab Laboratories, Tampere, Finland | Helsinki University Central Hospital, Helsinki, Finland | University of Foggia, Italy | National Research Council (CNR), Avellino, Italy | University of Tampere | Oslo University Hospital, Norway | Norwegian Institute of Public Health, Oslo, Norwa | University of Bonn, Bonn, Germany | University of Warmia and Mazury, Olsztyn, Poland | Montana State University, Bozeman, Montana | Medical University of Vienna, Vienna, Austria | Second University of Naples, Naples, Italy | University of Copenhagen, Hellerup, Denmark | Necker Children's Hospital, Paris, France | Paracelsus Private Medical University Salzburg, Austria | Medical University of Innsbruck, Austria | Krankenanstalt Rudolfstiftung, Wien, Austria | Bispebjerg University Hospital, Copenhagen, Denmark | University of Lille, France |